实验室负责人：黄学辉 教授
黄学辉，上海师范大学生命科学学院教授，博士生导师。建成了一整套全新的计算生物学方法,在水稻等作物的全基因组遗传变异鉴定、复杂农艺性状的遗传基础解析、杂种优势机理的分析方面取得了重要进展，成果以通迅作者发表在Nature，Nature Genetics等期刊。兼任Plant Biotechnology Journal、Science China Life Sciences、Journal of Integrative Plant Biology、Journal of Genetics and Genomics、Rice、Molecular Breeding等期刊副主编或编委。获得国家自然科学一等奖、张海银种业促进奖一等奖
学术团队
教 授：黄学辉
研究员：魏鑫
副研究员：邱杰、周晓艺
助理研究员：王勤、陈素卉、刘杰
研究方向：
1. 作物杂种优势的分子机理
2. 作物复杂性状的遗传解析与生产应用
3. 基因组学大数据的计算生物学方法开发
代表性科研项目：
1. 国家自然科学基金杰出青年基金项目：水稻数量遗传学研究, 基金委，2019-2023；
2. 国家重点研发计划青年科学家项目，水稻资源节约型性状优异基因挖掘及其分子设计， 2022-2025
3. 国家重点研发计划“合成生物学”重点专项，基于植物底盘的药用植物活性成分研究及其应用（2018YFA0900600），2019-2024
代表性论文：
1. Chen J, Tan C, Zhu M, Zhang C, Wang Z, Ni X, Liu Y, Wei T, Wei X, Fang X, Xu Y, Huang X, Qiu J*, Liu H* 1(2023) CropGS-Hub: a comprehensive database of genotype and phenotype resources for genomic prediction in major crops, Nucleic Acids Research, gkad1062, https://doi.org/10.1093/nar/gkad1062
2. Shi J*, Tian Z, Lai J, Huang X*. (2023) Plant pangenomes and its applications. Mol Plant 16:168-186
3. Junpeng Shi*, Zhixi Tian, Jinsheng Lai, Huang X*. (2023) Plant pangenomes and its applications. Mol Plant. 16:168-186
4. Wang Q, Fan J, Cong J, Chen M, Qiu J, Liu J, Zhao X, Huang R, Liu H, Huang X*. (2022) Natural variation of ZmLNG1 alters organ shapes in maize. New Phytol 237(2):471-482.
5. Junpeng Shi*, Zhixi Tian, Jinsheng Lai, Huang X*. (2023) Plant pangenomes and its applications. Mol Plant. 16:168-186
6. Zhang Q, Zhang S, X Yu, Wei X, Huang X, Zhou X*. (2022) Fine-tuning grain amylose contents by genome editing of Waxy cis-regulatory region in rice. Mol Breeding 42:72.
7. Huang X*, Huang S*, Han B, Li J*. (2022) The integrated genomics of crop domestication and breeding. Cell 185:2828-2839.
8. 作物杂种优势研究现状与展望，刘杰，黄学辉*。中国科学-生命科学，(2021)51:1396-1404
9. Zhang Sinan, Huang X*, Han B*. (2021) Understanding the genetic basis of rice heterosis: Advances and prospects. Crop J. 9:688-692
10. Wei X#, Qiu J#, Yong K, Fan J, Zhang Q, Hua H, Liu J, Wang Q, Olsen K M, Han B, Huang X*. A quantitative genomics map of rice provides genetic insights and guides breeding. Nat Genet 53:243-253 (2021).
11. ChenMengjiao#, Fan W#, Ji F#, Hua H, Liu J, Yan M, Ma Q, Fan J, Wang Q, Zhang S, Liu G, Sun Z, Tian C, Zhao F, Zheng J, Zhang Q, Chen J, Qiu J, Wei X, Chen Z, Zhang P*, Pei D*, Yang J*, Huang X*. (2021) Genome-wide identification of agronomically important genes in outcrossing crops using OutcrossSeq. Mol Plant 14:556-570.
12. Liu Jie, Li M, Zhang Q, Wei X, Huang X*. Exploring the molecular basis of heterosis for plant breeding. J Integr Plant Biol. 62:287-298 (2020).
13. Zhou Xiaoyi, Huang X*. Genome-wide Association Studies in Rice: How to Solve the Low Power Problems? Mol. Plant 12:10-12 (2019).
4. Zhao Qiang#, Feng Q#, Lu H, Li Y, Wang A, Tian Q, Zhan Q, Lu Y, Zhang L, Huang T, Wang Y, Fan D, Zhao Y, Wang Z, Zhou C, Chen J, Zhu C, Li W, Weng Q, Xu Q, Wang ZX, Wei X, Han B, Huang X*. Pan-genome analysis highlights the extent of genomic variation in cultivated and wild rice. Nat Genet. 50: 278-284 (2018).
5. Huang Xuehui*#, Yang S#, Gong J#, Zhao Q, Feng Q, Zhan Q, Zhao Y, Li W, Cheng B, Xia J, Chen N, Huang T, Zhang L, Fan D, Chen J, Zhou C, Lu Y, Weng Q, Han B*. Genomic architecture of heterosis for yield traits in rice. Nature 537:629-633 (2016).