实验室负责人：王文琴 教授
王文琴，上海师范大学生命科学学院教授，遗传学硕士生导师。2000毕业于兰州大学，获生物学学士学位；2003年毕业于中国疾病预防控制中心，获免疫学硕士学位；2013年毕业于美国新泽西州立大学，获植物学博士学位；2013-2015年在美国新泽西州立大学从事博士后研究。2015年进入上海交通大学工作，2021年入职上海师范大学。先后主持过国家自然科学基金面上项目、科技部重点研发计划和转基因重大专项。通信作者共发表SCI论文10多篇，包括Nature Communications, PNAS, Plant Biotechnology Journal, BMC Genomics等学术期刊，获国内发明专利1项。现任Frontiers in Genetics和Scientific Data杂志Editor。
学术团队
教 授： 王文琴
邮箱：wang2021@shnu.edu.cn
研究方向：
玉米是世界上最重要的粮食作物之一，我们利用基因组学以及转录组学等多组学工具解析农作物玉米胚乳发育过程中淀粉和蛋白质表达调控网络，为改善玉米籽粒的淀粉与蛋白的分配平衡和提升其品质提供理论基础。
代表性科研项目：
1. 优质蛋白玉米修饰增强子的基因克隆和功能解析；国家自然科学基金面上项目；2021-2024；59万，项目负责人。
2. 浮萍休眠期储存物质淀粉合成的转录调控；国家自然科学基金面上项目；2017-2020；60万，项目负责人。
3. 玉米高甲硫氨酸基因的克隆及育种; 科技部转基因重大专项子课题；2020-2021；50万，子课题负责人。
4. 玉米营养品质形成与改良的分子基础；科技部重点研发计划；2016-2020；90.85万；子课题负责人。
代表性论文：
1. Yang T, Wu X, Wang W & Wu Y*. (2023) Regulation of seed storage protein synthesis in monocot and dicot plants:A comparative review. Mol Plant 16, 145-167.
2. Fu Y, Xiao W, Tian L, Guo L, Ma G,Ji C, Huang Y, Wang H, Wu X, Yang T, Wang J, Wang J, Wu Y*, Wang W*.(2023) Spatial transcriptomics uncover sucrose post-phloem transport during maize kernel development. Nat Commun 14, 7191.
3. Fu Y, Li S, Xu L, Ji C, Xiao Q, Shi D, Wang G, Wang W, Wang J, Wang J*, Wu Y. (2023) RNA sequencing of cleanly isolated early endosperms reveals coenocyte-to-cellularization transition features in maize. Seed Biology 2:8
4. Huang Y, Wang H, Zhu Y, Huang X, Li S, Wu X, Zhao Y, Bao Z, Qin L, Jin Y, Cui Y, Ma G, Xiao Q, Wang Q, Wang J, Yang X, Liu H, Lu X, Larkins B, Wang W* and Wu Y*. (2022) THP9 enhances seed protein content and nitrogen-use efficiency in maize. Nature 612(7939):292-300.
5. Yang T, Wang H, Guo L, Wu X, Xiao Q, Wang J, Wang Q, Ma G, Wang W, Wu Y* (2022). ABA-induced Phosphorylation of basic Leucine Zipper 29, ABSCISIC ACID INSENSITIVE 19 and Opaque2 by SnRK2.2 Enhances Gene Transactivation for Endosperm Filling in Maize. Plant Cell 34(5):1933-1956
6. Zhao Z, Li S, Ji C, Zhou Y, Li C, Wang W*. Genetic Variation of the Serine Acetyltransferase Gene Family for Sulfur Assimilation in Maize. Genes 2021, 12.
7. Li C, Xiang X, Huang Y, Zhou Y, An D, Dong J, Zhao C, Liu H, Li Y, Wang Q, Du C, Messing J, Larkins BA, Wu Y*, Wang W*. Long-read sequencing reveals genomic structural variations that underlie creation of quality protein maize. Nature Communications 2020，11.
8. Zhang Y, An D, Li C, Zhao Z, Wang W*. The complete chloroplast genome of greater duckweed (Spirodela polyrhiza 7498) using PacBio long reads: insights into the chloroplast evolution and transcription regulation. BMC Genomics 2020, 21.
9. An D, Zhou Y, Li C, Xiao Q, Wang T, Zhang Y, Wu Y, Li Y, Chao DY, Messing J*, Wang W*. Plant evolution and environmental adaptation unveiled by long-read whole-genome sequencing of Spirodela. Proc Natl Acad Sci USA 2019, 116.
10. Zhou Y, Zhao Z, Zhang Z, Fu M, Wu Y, Wang W*. Isoform sequencing provides insight into natural genetic diversity in maize. Plant Biotechnology Journal 2018, 17.
11. Li C, Huang Y, Huang R, Wu Y, Wang W*. The genetic architecture of amylose biosynthesis in maize kernel. Plant Biotechnology Journal 2017, 16(2).
12. An D, Li C, Zhou Y, Wu Y, Wang W*. Genomes and Transcriptomes of Duckweeds. Front Chem 2018, 6.
13. An D, Cao HX, Li C, Humbeck K, Wang W*. Isoform Sequencing and State-of-Art Applications for Unravelling Complexity of Plant Transcriptomes. Genes 2018,9.
14. Wang W, Haberer G, Gundlach H, Glasser C, Nussbaumer T, Luo MC, Lomsadze A, Borodovsky M, Kerstetter RA, Shanklin J, Michael TP, Mayer K F, Messing J*. The Spirodela polyrhiza genome reveals insights into its neotenous reduction fast growth and aquatic lifestyle. Nature Communications 2014, 5